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Vaccines are formulated to stimulate a protective immune response, while minimizing the potential for negative side-effects on exposure to the recipient. Vaccine formulation is complex and should be tightly regulated to maximize safety. Creative Biolabs is expert in formulation development. Our formulation optimization strategies can provide you with the best advice and accelerate your vaccine development program.

The stability of vaccine components in solution is a direct function of several environmental conditions that ultimately contribute to the measurable physicochemical properties of the critical biomolecules. Most significant are solution pH, ionic strength, redox potential, and temperature, all of which often contribute directly to the stability of macromolecules. In addition, more pharmaceutical variables such as agitation and freeze/thaw stress, as well as surface activity, may all play key roles in formulation considerations.